
Cefamandole nafate
CAS No. 42540-40-9
Cefamandole nafate ( Cephamandole nafate | Cefamandole formate sodium )
产品货号. M19801 CAS No. 42540-40-9
头孢孟多钠是第二代广谱头孢菌素抗生素。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
25MG | ¥324 | 有现货 |
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100MG | ¥640 | 有现货 |
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500MG | ¥1272 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Cefamandole nafate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述头孢孟多钠是第二代广谱头孢菌素抗生素。
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产品描述Cefamandole nafate is a second-generation broad-spectrum cephalosporin antibiotic.(In Vitro):Cefamandole nafate is shown to be rapidly converted to cefamandole in bacteriological media, with a half-life of less than 1 h at a pH of 7.0 or above. At pH 6.0, in log-phase inhibition experiments, however, Cefamandole nafate is more stable, allowing delineation of the activity between cefamandole and cefamandole nafate.(In Vivo):The toxicity of Cefamandole nafate administered iv Is studied in rats receiving doses of 250-1,000 mg/kgfive days per week for one month.After the administration of Cefamandole nafate for one month, there are no treatment-related adverse effects on growth, food consumption, clinical chemistry, hematology, or organ weights.
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体外实验Cefamandole nafate is shown to be rapidly converted to cefamandole in bacteriological media, with a half-life of less than 1 h at a pH of 7.0 or above. At pH 6.0, in log-phase inhibition experiments, however, Cefamandole nafate is more stable, allowing delineation of the activity between cefamandole and cefamandole nafate.
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体内实验The toxicity of Cefamandole nafate administered iv Is studied in rats receiving doses of 250-1,000 mg/kg five days per week for one month.After the administration of Cefamandole nafate for one month, there are no treatment-related adverse effects on growth, food consumption, clinical chemistry, hematology, or organ weights.
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同义词Cephamandole nafate | Cefamandole formate sodium
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通路GPCR/G Protein
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靶点Antibacterial
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受体Bacterial
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研究领域Inflammation/Immunology
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适应症Pulmonary infection urinary tract infection biliary tract infection skin and soft tissue infection bone and joint infection
化学信息
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CAS Number42540-40-9
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分子量512.49
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分子式C19H17N6NaO6S2
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 41 mg/mL (80.00 mM);Water:≥ 29 mg/mL (56.59 mM)
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SMILES[Na+].Cn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](OC=O)c1ccccc1)C2=O)C([O-])=O
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化学全称sodium;(6R7R)-7-[[(2R)-2-formyloxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Taha M. et al.: Bioorg. Med. Chem. 16 1218 (2008)
产品手册




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